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Description |
The LnLCorr package is designed
to detect pairwise coevolutionary among residues in a set of proteins
using likelihood ratio tests. The basic program was described
in Pollock, Taylor, and Goldman (1999), and only minor modifications
have been made since. |
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Downloading |
A set of Linux executables, control
files, and example files (.tar) may be downloaded here.
Future versions may be compiled on various platforms. We hope
to release a GNU version of the code soon. Please contact us for
compiling on alternate platforms. A Linux version that does not
require pdb files is here (To use
these, you need to delete the pdb file name).
NEW: You
will also want a version of CorrStrap_nopdb that does not require pdb files).
NEW: Two
versions of CorrStrap and LnLCorr are available with statically linked libraries, which may be useful
for runing on older versions of Linux that may not have all the
libraries that LnLCorr requires. |
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Manual |
Available here.
It is pretty brief at this time, so please contact us with questions
or requests. |
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Images |
Two movies of coevolving sites in COI are available (Wang and Pollock, 2007, in press ). Warning: some of these images are around 20 MB. |
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Credits |
Original concept and programming by
D Pollock, with input from WR Taylor and N Goldman. Current development
by Z Wang and D Pollock. A parallel version is in the testing stage
and may be available soon. |
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References |
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Wang, Z.O., and D. D. Pollock, “Coevolutionary patterns in cytochrome c oxidase subunit I depend on structural and functional context .” Journal of Molecular Evolution in press (2007).
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