Pollock laboratory programs

 

PROGRAMS

Programs are released by the Pollock Laboratory under a "use at your own risk" policy. They are mostly designed as research instruments rather than as user-friendly processed applications. They are generally written in C (some with perl wrappers and text-processors, and some with complementary R script for visualization of results) and operate using control files. Usually the graduate students(s) or postdoc(s) who have written the programs are likely to be most helpful in getting them to work.

PLEX

Phylogenetics, Likelihood, Evolution, and CompleXity

A program for rapid likelihood analysis on large phylogenies using partial sampling of substitution histories.

PClouds

Identify repeat structure in large eukaryotic genomes using oligonucleotide counts. It works efficiently on a single desktop computer with 1 Gb memory.

SULDEX

Use high throughput sequencing to simultaneously analyze binding dissociation constants for large repertoires of sequences.

TFCoEvolve

Three programs used to analyze coevolution of transcription factor binding sites.

 

LnLCorr

Detect pairwise coevolutionary among residues in a set of proteins using likelihood ratio tests. Note: This link is largely historical. Updates to this program have since been made and are available upon request from Zhengyuan Wang. Myoglobin data used in the 1999 paper are also available.

Convergence

Convergence/Divergence code from Castoe et al 2009 for use with codeml.

 

David Pollock David Pollock Todd Castoe

Wanjun Gu

compbio compbio